Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822719 | 0.95 | PTPN1 (0.48) | PTPN1ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL6923219 | 0.90 | PTPN1 (0.51) | PTPN1ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL6826038 | 0.81 | THRB (0.46) | ALDH1A1TDP1MAPTKMT2AS100A4 | |
| SCHEMBL6826057 | 0.80 | S100A4 (0.46) | S100A4THRBMAPK1LMNAKDM4E | |
| SCHEMBL15153190 | 0.79 | ALDH1A1 (0.50) | PTPN1ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL6826041 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TDP1MAPTTHRBMAPK1 | |
| SCHEMBL4855882 | 0.74 | PTGS2 (0.49) | PTPN1ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL28422058 | 0.73 | CYP2A6 (0.40) | TDP1MAPTKMT2ACYP3A4CYP2C9 | |
| SCHEMBL4849981 | 0.73 | PTGS2 (0.48) | PTPN1ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL18329006 | 0.72 | MAPT (0.47) | PTPN1ALDH1A1TDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096766-A1 | A METHOD OF INDOLE SYNTHESIS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2004-11-11 | — | — | WO | disclosed |