Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411085 | 0.88 | KMT2A (0.47) | KMT2AMEN1NPSR1PTPN2PTPN1 | |
| SCHEMBL7342541 | 0.85 | EPHX2 (0.50) | KMT2AMEN1NPSR1POLBLMNA | |
| SCHEMBL5370476 | 0.85 | LMNA (0.45) | GAAPOLBMMP8LMNAMAPT | |
| SCHEMBL1239980 | 0.85 | POLB (0.52) | KMT2AMEN1GAAPOLBMMP8 | |
| SCHEMBL5365539 | 0.81 | CA1 (0.48) | GAALMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL12921405 | 0.81 | SMN1; SMN2 (0.47) | KMT2AMEN1LMNAMAPK1 | |
| SCHEMBL15767792 | 0.78 | EPHX2 (0.50) | GAAPOLBALDH1A1TSHRMME | |
| SCHEMBL27747 | 0.78 | MMP8 (0.58) | KMT2AMEN1NPSR1MMP8LMNA | |
| SCHEMBL13721030 | 0.78 | EPHX2 (0.49) | KMT2AMEN1NPSR1POLBMMP8 | |
| SCHEMBL12894592 | 0.78 | LMNA (0.58) | LMNAALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518260-B1 | (α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2003-02-11 | — | — | US | disclosed |
| US-6391866-B1 | ANALGESICS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-05-21 | — | — | US | disclosed |