⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56720 | 0.78 | — | — | |
| SCHEMBL766382 | 0.76 | — | — | |
| SCHEMBL21858258 | 0.76 | — | — | |
| SCHEMBL1513790 | 0.76 | — | — | |
| SCHEMBL2600786 | 0.74 | TSHR (0.38) | — | |
| SCHEMBL17489116 | 0.74 | TSHR (0.38) | — | |
| SCHEMBL2358428 | 0.74 | — | — | |
| SCHEMBL8400578 | 0.74 | TSHR (0.38) | — | |
| SCHEMBL4219834 | 0.74 | — | — | |
| SCHEMBL6962867 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487481-A1 | COMPOSITIONS COMPRISING A POLYSACCHARIDE MATRIX FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS | Jointherapeutics S.r.l. (IT) | 2019-05-29 | — | — | EP | claimed |
| EP-3364947-A1 | AQUEOUS COMPOSITION COMPRISING DANTROLENE | B. Braun Melsungen AG (DE) | 2018-08-29 | — | — | EP | claimed |
| WO-2018015364-A1 | COMPOSITIONS COMPRISING A POLYSACCHARIDE MATRIX FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS | JOINTHERAPEUTICS S.R.L. (IT) | 2018-01-25 | — | — | WO | claimed |
| WO-2017067980-A1 | AQUEOUS COMPOSITION COMPRISING DANTROLENE | B. BRAUN MELSUNGEN AG (DE) | 2017-04-27 | — | — | WO | claimed |
| EP-3621963-B1 | COMPOUNDS FOR THE TREATMENT OF EPILEPSY, NEURODEGENERATIVE DISORDERS AND OTHER CNS DISORDERS | REMYND N V (BE) | 2024-01-24 | — | — | EP | disclosed |
| WO-2023241799-A1 | FLAVANOLS FOR USE IN THE TREATMENT OF RETROVIRAL INFECTIONS | Université Libre de Bruxelles (BE) | 2023-12-21 | — | — | WO | disclosed |
| EP-4110777-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | Katholieke Universiteit Leuven, K.U.Leuven R&D (BE) | 2023-01-04 | — | — | EP | disclosed |
| EP-3180003-B1 | PKC-EPSILON INHIBITORS | UNIV CALIFORNIA (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3621963-A1 | COMPOUNDS FOR THE TREATMENT OF EPILEPSY, NEURODEGENERATIVE DISORDERS AND OTHER CNS DISORDERS | Remynd N.V. (BE) | 2020-03-18 | — | — | EP | disclosed |
| WO-2018206760-A1 | COMPOUNDS FOR THE TREATMENT OF EPILEPSY, NEURODEGENERATIVE DISORDERS AND OTHER CNS DISORDERS | REMYND N.V. (BE) | 2018-11-15 | — | — | WO | disclosed |
| CN-107964013-A | Antifungal agent | 詹森药业有限公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-103228659-B | Benzene derivative substituted 5, 6-dihydro-4H-pyrrolo [1,2-A ] [1,4] benzodiazepine and 6H-pyrrolo [1,2-A ] [1,4] benzodiazepine antifungal agent | 詹森药业有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-1330643-A | IL-5 inhibiting azauracil pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2002-01-09 | — | — | CN | disclosed |
| CN-1261881-A | 6-azauracil derivatives as IL-5 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2000-08-02 | — | — | CN | disclosed |
| CN-1236366-A | Amino acid ester-containing azole antifungal agents | JANSSEN PHARMACEUTICA NV (BE) | 1999-11-24 | — | — | CN | disclosed |
| CN-1041726-C | 1.3-Dihydro-2H-Imidazo{4,5-6} Quinolin-2-One derivatives. | JANSSEN PHARMACEUTICA NV (BE) | 1999-01-20 | — | — | CN | disclosed |
| CN-1200122-A | Lubeluzole N-oxide | JANSSEN PHARMACEUTICA NV (BE) | 1998-11-25 | — | — | CN | disclosed |
| CN-1148335-A | Mucoadhesive emulsions containing cyclodextrins | JANSSEN PHARMACEUTICA NV (BE) | 1997-04-23 | — | — | CN | disclosed |
| CN-1136776-A | Oral formulations of antifungal | JANSSEN PHARMACEUTICA NV (BE) | 1996-11-27 | — | — | CN | disclosed |
| CN-1072681-A | 1,3-dihydro-2H-imidazo [4,5-b] quinoline-2-one-derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1993-06-02 | — | — | CN | disclosed |