SCHEMBL2600786

SCHEMBL2600786

CC(OCC(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
CTH P32929 1/20 0.38
CBS P35520 1/20 0.38
THPO P40225 1/20 0.38
CYP1A2 P05177 2/20 0.37
TP53 P04637 1/20 0.36
THRB P10828 1/20 0.36
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL585968 0.95 TSHR (0.35) TSHRCTHCBSTHPOCYP1A2
SCHEMBL29016960 0.82 TDP1 (0.36) CYP1A2TP53ALDH1A1GAACYP2C9
SCHEMBL6645229 0.82 TSHR (0.36) TSHRCTHCBSTHPOCYP1A2
SCHEMBL7159806 0.82 TDP1 (0.36) CYP1A2TP53ALDH1A1GAACYP2C9
SCHEMBL29016903 0.82 TDP1 (0.36) CYP1A2TP53ALDH1A1GAACYP2C9
SCHEMBL11658193 0.80 GABRR1 (0.34) TP53KMT2A
SCHEMBL9312771 0.78 SMN1; SMN2 (0.38) TSHRCTHCBSTHPOTHRB
SCHEMBL1025317 0.78 TSHR (0.34) TSHRTP53
SCHEMBL31634142 0.78 TSHR (0.40) TSHRCYP1A2TP53ALDH1A1GAA
SCHEMBL29016924 0.78 TSHR (0.34) TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115504901-B [A336] method for preparing nuclear-grade zirconium and nuclear-grade hafnium by extracting and separating [ DGA ] type ionic liquid in acidic system 厦门稀土材料研究所 2024-08-09 CN disclosed
CN-114588861-B Furanone preparation system and furanone preparation method 宁夏万香源生物科技有限公司 2024-04-26 CN disclosed
CN-114720606-A Method for determining content of organic heteropolyacid in glycolic acid by gas chromatography 内蒙古久泰新材料有限公司 2022-07-08 CN disclosed
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 US disclosed
CN-101679749-B The silicon composition of rapid deep-section cure MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-05-25 CN disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-19 US disclosed
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-19 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20080027144-A1 Benzonaphthacene Glycoside Derivative and Use Thereof FUJIFILM CORPORATION (JP) 2008-01-31 US disclosed
US-4153726-A Skin protection agents containing polyethercarboxylic acids HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-05-08 US disclosed
US-3956383-A HEAVY METAL CATALYST HENKEL & CIE G.M.B.H. (DT) 1976-05-11 US disclosed
US-3956381-A CARBOXYLATION, 1A METAL ALKYL CARBONATE HENKEL & CIE G.M.B.H. (DT) 1976-05-11 US disclosed
US-3956382-A CARBOXYLATION, 1A METAL CARBONATES, BICARBONATES, OR HYDROXIDES HENKEL & CIE G.M.B.H. (DT) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 TSHR 2565/4885CTH 1558/4885CBS 2359/4885
US-20080027144-A1 Benzonaphthacene Glycoside Derivative and Use Thereof SORD, PSAT1, SBDS TSHR 4691/4885CTH 1116/4885CBS 1429/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TSHR 2352/4885CTH 973/4885CBS 1371/4885
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS MME, CTSA, ALG1 TSHR 3963/4885CTH 2044/4885CBS 1595/4885
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH TSHR 4423/4885CTH 3405/4885CBS 1992/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TSHR 2352/4885CTH 973/4885CBS 1371/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 TSHR 2352/4885CTH 973/4885CBS 1371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.