Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922965 | 0.81 | THRB (0.48) | THRBMCL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6645931 | 0.78 | THRB (0.53) | THRBMCL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6645076 | 0.76 | THRB (0.50) | THRBMCL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6488813 | 0.76 | MAPT (0.47) | MAPTMCHR1NPC1MEN1KMT2A | |
| SCHEMBL6645869 | 0.75 | PRKAB2 (0.50) | THRBMCL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6645353 | 0.74 | THRB (0.51) | THRBMCL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6645303 | 0.74 | THRB (0.48) | THRBMCL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6647724 | 0.73 | THRB (0.48) | THRBPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL6644406 | 0.72 | THRB (0.53) | THRBMCL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6645791 | 0.72 | THRB (0.52) | THRBMCL1PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |