Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928804 | 0.89 | TRPV4 (0.31) | — | |
| SCHEMBL7648893 | 0.87 | TAS2R14 (0.31) | — | |
| SCHEMBL6929437 | 0.85 | POLB (0.33) | CA1CA2CA12CA4CA5A | |
| SCHEMBL7648880 | 0.85 | CNR2 (0.32) | KDM4EALDH1A1POLB | |
| SCHEMBL7647679 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL6928527 | 0.84 | PARP1 (0.40) | CACNA1H | |
| SCHEMBL7648078 | 0.84 | KDM4E (0.36) | KDM4EALDH1A1POLB | |
| SCHEMBL6926873 | 0.83 | USP2 (0.38) | CA1CA2CA12CA4CA5A | |
| SCHEMBL6927437 | 0.82 | CA1 (0.41) | CA1CA2CA12CA4CA5A | |
| SCHEMBL7198556 | 0.80 | CA12 (0.33) | CA1CA2CA12CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596709-B1 | For treatment of Alzheimer's disease, schizophrenia, amyotrophic lateral sclerosis, and Huntington's chorea | LES LABORATOIRES SERVIER (FR) | 2003-07-22 | — | — | US | disclosed |
| US-6518258-B1 | 6-sulphamoyl -3-quinolyphosphonic acid compounds | LES LABORATOIRES SERVIER (FR) | 2003-02-11 | — | — | US | disclosed |
| CN-1317490-A | Novel-6-sulfamine-3-quinolyl phosphonate compounds, its prepn. process and medical compsn. contg. them | ADIR (FR) | 2001-10-17 | — | — | CN | disclosed |