Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927078 | 0.89 | KDM4E (0.45) | KDM4EPKMGPR119ACHETGFBR1 | |
| SCHEMBL6929452 | 0.88 | TLR7 (0.54) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6926916 | 0.87 | CSF1R (0.44) | KDM4EPKMGPR119 | |
| SCHEMBL6926177 | 0.82 | TLR7 (0.53) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL4338051 | 0.81 | TLR7 (0.40) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6096772 | 0.78 | TLR7 (0.56) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3862340 | 0.78 | TLR7 (0.59) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3751306 | 0.77 | PI4KA (0.50) | ADORA2AMAP4K4TGFBR1 | |
| Hydrochloric Acid SCHEMBL6929408 | 0.77 | TLR7 (0.55) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6862807 | 0.77 | TLR7 (0.58) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |