Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6929408 | 0.99 | TLR7 (0.55) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL12631901 | 0.88 | TLR7 (0.52) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6925999 | 0.87 | ACHE (0.43) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6838687 | 0.85 | HTR4 (0.41) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6929452 | 0.83 | TLR7 (0.54) | TLR7LMNAPOLBHRH2ADRA1D | |
| Trifluoroacetic Acid SCHEMBL6928326 | 0.80 | NR3C1 (0.45) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL1140794 | 0.79 | LMNA (0.49) | LMNAHTR4TSHRHTTNPSR1 | |
| SCHEMBL3197872 | 0.79 | TLR7 (0.59) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6926177 | 0.79 | TLR7 (0.53) | TLR7LMNAPOLBHRH2ADRA1D | |
| Water SCHEMBL9602607 | 0.78 | TLR7 (0.58) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | claimed |
| US-7112677-B2 | 1H-imidazo dimers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-09-26 | — | — | US | disclosed |
| EP-1542688-A2 | 1H-IMIDAZO DIMERS | 3M Innovative Properties Company (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20050026947-A1 | 1H-imidazo dimers | 3M INNOVATIVE PROPERTIES COMPANY | 2005-02-03 | — | — | US | disclosed |
| US-6818650-B2 | 1H-IMIDAZO(4,5-C)- QUINOLINE OR -PYRIDINE DERIVATIVES; INDUCE BIOSYNTHESIS OF CYTOKINES; VIRAL DISEASES; ANTICARCINOGENIC AND ANTITUMOR AGENTS; IMMUNOMODULATORS | 3M INNOVATIVE PROPERTIES COMPANY | 2004-11-16 | — | — | US | disclosed |
| US-20040132766-A1 | 1H-imidazo dimers | 3M INNOVATIVE PROPERTIES COMPANY | 2004-07-08 | — | — | US | disclosed |
| WO-2004028539-A2 | 1H-IMIDAZO DIMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-04-08 | — | — | WO | disclosed |
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026947-A1 | 1H-imidazo dimers | IL2, EIF2AK2, IRF3 | TLR7 173/4885LMNA 4369/4885POLB 2556/4885 |
| US-20040132766-A1 | 1H-imidazo dimers | IL2, EIF2AK2, IRF3 | TLR7 173/4885LMNA 4369/4885POLB 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.