SCHEMBL6926916

SCHEMBL6926916

CC(C)(C)OC(=O)N1CCC(CCn2cnc3c(Oc4ccccc4)nc4ccccc4c32)CC1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 2/20 0.44
KDR P35968 1/20 0.44
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.43
PDE10A Q9Y233 1/20 0.42
GPR119 Q8TDV5 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6929721 0.89 ACHE (0.43)
SCHEMBL6923675 0.87 TLR7 (0.53) KDM4EPKMGPR119
SCHEMBL6927078 0.87 KDM4E (0.45) KDM4EPKMGPR119
SCHEMBL6928736 0.82 ACP1 (0.42)
SCHEMBL6925393 0.75 ACHE (0.46)
SCHEMBL6929452 0.74 TLR7 (0.54)
SCHEMBL6702926 0.74 TLR7 (0.44) KDM4E
SCHEMBL6837673 0.72 HPGDS (0.47) KDM4EPKMGPR119
SCHEMBL6838678 0.72 KDM4E (0.43) KDM4EPKMGPR119
SCHEMBL2158159 0.71 GPR119 (0.65) CSF1RKDRKDM4EPKMGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed