SCHEMBL692382

SCHEMBL692382

COC(=O)C1C2CC3CC(C2)CC1(C(=O)OC)C3

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.37
CHRNB2 P17787 2/20 0.36
CHRNA4 P43681 2/20 0.36
EPHX2 P34913 3/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CNR2 P34972 1/20 0.32
CCR6 P51684 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21753386 0.79 ALDH1A1 (0.40) ALDH1A1L3MBTL1GLAEPHX2MEN1
SCHEMBL27730301 0.77 ALDH1A1 (0.39) ALDH1A1L3MBTL1GLAEPHX2MEN1
SCHEMBL11344046 0.77 ALDH1A1 (0.42) ALDH1A1L3MBTL1GLAEPHX2MEN1
SCHEMBL5433897 0.77 MAPK1 (0.40) EPHX2MEN1KMT2A
Hydrochloric Acid SCHEMBL11330580 0.76 ALDH1A1 (0.41) ALDH1A1L3MBTL1GLAEPHX2MEN1
SCHEMBL8709524 0.76 GLA (0.43) ALDH1A1L3MBTL1GLAEPHX2MEN1
SCHEMBL3682434 0.76 CYP3A4 (0.43) ALDH1A1EPHX2
SCHEMBL6355127 0.71 EPHX2 (0.35) EPHX2
SCHEMBL6354528 0.71 SLC22A2 (0.35) ALDH1A1EPHX1
SCHEMBL3957946 0.70 ALDH1A1 (0.36) ALDH1A1L3MBTL1GLAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421904-B1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD GRACE W R & CO (US) 2015-06-24 EP disclosed
US-8288304-B2 Procatalyst composition with adamantane and method DOW GLOBAL TECHNOLOGIES LLC (US) 2012-10-16 US disclosed
EP-2421904-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD Dow Global Technologies LLC (US) 2012-02-29 EP disclosed
WO-2010123775-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-28 WO disclosed
US-20100273966-A1 Procatalyst Composition with Adamantane and Method W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed
US-7781540-B2 Resin composition and molded articles thereof OSAKA GAS CO., LTD. (JP) 2010-08-24 US disclosed
EP-1808461-B1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF TEIJIN CHEMICALS LTD (JP) 2009-03-11 EP disclosed
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20080085955-A1 Resin Composition And Molded Articles Thereof OSAKA GAS CO., LTD. (JP) 2008-04-10 US disclosed
EP-1808461-A1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF Teijin Chemicals, Ltd. (JP) 2007-07-18 EP disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed