Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924378 | 0.84 | MCHR1 (0.54) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL5132224 | 0.79 | MCHR1 (0.59) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL1486263 | 0.77 | GAA (0.54) | — | |
| SCHEMBL6925443 | 0.76 | MCHR1 (0.81) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6926161 | 0.76 | MCHR1 (0.76) | MCHR1HTR2C | |
| SCHEMBL6204180 | 0.75 | GAA (0.47) | MCHR1HTR2C | |
| SCHEMBL4033138 | 0.75 | SLC2A1 (0.65) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6920748 | 0.75 | MCHR1 (0.71) | MCHR1HTR2C | |
| SCHEMBL6926745 | 0.75 | MCHR1 (0.71) | MCHR1HTR2C | |
| SCHEMBL7067789 | 0.75 | MCHR1 (0.66) | MCHR1HTR2CSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001766-B1 | COMPOUNDS FOR THE TREATMENT OF CCR5-MEDIATED DISEASES | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6515027-B1 | Ligands, agonists or antagonists, of the CC chemokine receptor CC-CKR5 | SMITHKLINE BEECHAM CORP. | 2003-02-04 | — | — | US | disclosed |