Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.65 |
| ▸ | MCHR1 | Q99705 | 18/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450293 | 0.83 | EGFR (0.58) | MCHR1 | |
| SCHEMBL14260335 | 0.83 | MAPT (0.59) | — | |
| SCHEMBL5043916 | 0.80 | TGM2 (0.63) | — | |
| SCHEMBL5132224 | 0.79 | MCHR1 (0.59) | SLC2A1MCHR1HTR2C | |
| SCHEMBL7613674 | 0.79 | SLC2A1 (0.81) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL7613669 | 0.79 | SLC2A1 (0.81) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL28455574 | 0.78 | EGFR (0.58) | — | |
| SCHEMBL7606654 | 0.78 | SLC2A1 (0.68) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL7606657 | 0.78 | SLC2A1 (0.68) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL28463718 | 0.78 | EGFR (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648448-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-04-01 | — | — | EP | disclosed |
| US-20080058515-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-03-06 | — | — | US | disclosed |
| EP-1648448-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005011681-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058515-A1 | Chemical Compounds | SGK1, SGK2, SGK3 | SLC2A1 2490/4885MCHR1 4225/4885HTR2C 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.