Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.52 |
| ▸ | TUBB | P07437 | 4/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538872 | 0.82 | KDM4E (0.70) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL3036356 | 0.82 | KDM4E (0.70) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL4877545 | 0.80 | KDM4E (0.67) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL31019418 | 0.78 | KDM4E (0.66) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL5220303 | 0.78 | KDM4E (0.66) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL5193898 | 0.78 | KDM4E (0.64) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL7508184 | 0.78 | KDM4E (0.64) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL14174312 | 0.75 | KDM4E (0.60) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL3659426 | 0.75 | KDM4E (0.60) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL23873802 | 0.75 | ALDH1A1 (0.74) | KDM4EGAAHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111052-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE (MDR) | XENOVA LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |