Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931042 | 1.00 | TK1 (0.39) | TK1GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL6928564 | 0.91 | TK1 (0.38) | TK1KMT2ATYMPHPGDTK2 | |
| SCHEMBL6924148 | 0.91 | TK1 (0.38) | TK1KMT2ATYMPHPGDTK2 | |
| SCHEMBL8135550 | 0.90 | TK1 (0.37) | TK1GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL5358371 | 0.85 | TK1 (0.37) | TK1KMT2ATYMPHPGDTK2 | |
| SCHEMBL8150170 | 0.83 | TK1 (0.41) | TK1KMT2AHPGDTK2 | |
| SCHEMBL5349908 | 0.83 | TK1 (0.39) | TK1GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL5366400 | 0.80 | KMT2A (0.40) | TK1GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL6513732 | 0.80 | TK1 (0.38) | TK1KMT2ATYMPHPGDTK2 | |
| SCHEMBL6924142 | 0.80 | TK1 (0.38) | TK1KMT2ATYMPHPGDTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960121-A4 | PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY | BUCHARDT DORTE (DK) | 2003-05-28 | — | — | EP | disclosed |
| EP-0960121-A1 | PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY | BUCHARDT, Dorte (DK) | 1999-12-01 | — | — | EP | disclosed |
| US-5766855-A | Peptide nucleic acids having enhanced binding affinity and sequence specificity | BUCHARDT OLE (DK) | 1998-06-16 | — | — | US | disclosed |
| WO-1998003542-A1 | PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY | BUCHARDT, DORTE (DK) | 1998-01-29 | — | — | WO | disclosed |