SCHEMBL692427

SCHEMBL692427

Cc1ccc2nc(-c3cccs3)c(=O)[nH]c2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.68
NPC1 O15118 4/20 0.68
HSD17B10 Q99714 3/20 0.68
GLA P06280 2/20 0.68
LMNA P02545 1/20 0.68
CASP1 P29466 1/20 0.68
CASP7 P55210 1/20 0.68
ALDH1A1 P00352 6/20 0.48
HPGD P15428 5/20 0.48
MAPK1 P28482 1/20 0.48
KDM4E B2RXH2 5/20 0.48
MAPT P10636 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
TP53 P04637 3/20 0.47
KLK7 P49862 1/20 0.47
GAA P10253 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPK8 P45983 1/20 0.45
MAPK9 P45984 1/20 0.45
MAPK10 P53779 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15798267 0.84 HPGD (0.48) RAB9ANPC1HSD17B10GLALMNA
SCHEMBL1902708 0.83 HSD17B10 (0.64) RAB9ANPC1HSD17B10GLALMNA
SCHEMBL1509112 0.81 RAB9A (1.00) RAB9ANPC1HSD17B10GLALMNA
SCHEMBL30026859 0.81 RAB9A (1.00) RAB9ANPC1HSD17B10GLALMNA
SCHEMBL1898900 0.81 NPC1 (0.72) RAB9ANPC1HSD17B10GLALMNA
SCHEMBL12082222 0.80 RAB9A (0.69) RAB9ANPC1HSD17B10GLAALDH1A1
Hydrochloric Acid SCHEMBL30418554 0.80 RAB9A (0.97) RAB9ANPC1HSD17B10GLALMNA
SCHEMBL6261454 0.80 NPC1 (0.62) RAB9ANPC1HSD17B10GLALMNA
SCHEMBL2135032 0.80 LMNA (0.66) RAB9ANPC1HSD17B10GLALMNA
Hydrochloric Acid SCHEMBL16398714 0.78 RAB9A (0.60) RAB9ANPC1HSD17B10GLALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017186577-A1 TIMED-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME BAYER CROPSCIENCE AKTIENGESSELSCHAFT (DE) 2017-11-02 WO disclosed
EP-2958430-A1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES Bayer CropScience AG (DE) 2015-12-30 EP disclosed
WO-2014128069-A1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES BAYER CROPSCIENCE AG (DE) 2014-08-28 WO disclosed
WO-2014090765-A1 USE OF 1-[2-FLUORO-4-METHYL-5-(2,2,2-TRIFLUOROETHYLSULFINYL)PHENYL]-5-AMINO-3-TRIFLUOROMETHYL)-1 H-1,2,4 TFIA ZOLE FOR CONTROLLING NEMATODES IN NEMATODE-RESISTANT CROPS BAYER CROPSCIENCE AG (DE) 2014-06-19 WO disclosed
EP-2645856-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS AND FOR INCREASING YIELD Bayer Intellectual Property GmbH (DE) 2013-10-09 EP disclosed
EP-2618667-A2 USE OF BIOLOGICAL OR CHEMICAL CONTROL AGENTS FOR CONTROLLING INSECTS AND NEMATODES IN RESISTANT CROPS Bayer Intellectual Property GmbH (DE) 2013-07-31 EP disclosed
WO-2013092519-A1 USE OF ANTHRANILIC ACID DIAMIDE DERIVATIVES FOR PEST CONTROL IN TRANSGENIC CROPS BAYER CROPSCIENCE AG (DE) 2013-06-27 WO disclosed
WO-2012072660-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS AND FOR INCREASING YIELD BAYER CROPSCIENCE AG (DE) 2012-06-07 WO disclosed
WO-2012038480-A2 USE OF BIOLOGICAL OR CHEMICAL CONTROL AGENTS FOR CONTROLLING INSECTS AND NEMATODES IN RESISTANT CROPS BAYER CROPSCIENCE AG (DE) 2012-03-29 WO disclosed
EP-2421371-A1 USE OF PROPINEB AS BIRD REPELLENT Bayer CropScience AG (DE) 2012-02-29 EP disclosed
WO-2011107443-A1 USE OF PROPINEB FOR PHYSIOLOGICAL CURATIVE TREATMENT UNDER ZINC DEFICIENCY BAYER CROPSCIENCE AG (DE) 2011-09-09 WO disclosed
WO-2010121735-A1 USE OF PROPINEB AS BIRD REPELLENT BAYER CROPSCIENCE AG (DE) 2010-10-28 WO disclosed