Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065400 | 1.00 | MEN1 (0.47) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL4865057 | 1.00 | MEN1 (0.47) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL11468464 | 0.93 | MEN1 (0.45) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL1763291 | 0.90 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL13363848 | 0.90 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL23393883 | 0.90 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL1763221 | 0.90 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL13436114 | 0.90 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL1763293 | 0.90 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL25322420 | 0.85 | TSHR (0.46) | MEN1KMT2ASLC18A3SIGMAR1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959887-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE INC (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-0959887-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998006401-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-19 | — | — | WO | disclosed |