Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23393883 | 1.00 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL1763293 | 1.00 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL13363848 | 1.00 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL1763221 | 1.00 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL13436114 | 1.00 | MEN1 (0.50) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL14065400 | 0.90 | MEN1 (0.47) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL4865057 | 0.90 | MEN1 (0.47) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL6924404 | 0.90 | MEN1 (0.47) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL11468464 | 0.87 | MEN1 (0.45) | MEN1KMT2ASLC18A3SIGMAR1PRCP | |
| SCHEMBL19283462 | 0.86 | MEN1 (0.64) | MEN1KMT2APRCPKCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845078-B1 | PROCESS FOR PRODUCING LARGE CYCLIC KETONE AND INTERMEDIATE THEREFOR | TAKASAGO PERFUMERY CO LTD (JP) | 2017-06-07 | — | — | EP | disclosed |
| US-9233920-B2 | Process for the preparation of dihydropyrrole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-12 | — | — | US | disclosed |
| US-9233920-B2 | Process for the preparation of dihydropyrrole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-12 | — | — | US | disclosed |
| EP-2580211-B1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-19 | — | — | EP | disclosed |
| US-8759541-B2 | Chiral acyclic diaminocarbene ligands, precursors therefore and their use in organic synthesis reactions | THADANI AVINASH N (CA) | 2014-06-24 | — | — | US | disclosed |
| US-20130237583-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130237583-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-12 | — | — | US | disclosed |
| WO-2011154555-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-15 | — | — | WO | disclosed |
| US-20110118475-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | THADANI AVINASH N | 2011-05-19 | — | — | US | disclosed |
| US-7683191-B2 | Organic salts and method for producing chiral organic compounds | Studiangesellschaft Kohle mbH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-7683191-B2 | Organic salts and method for producing chiral organic compounds | Studiangesellschaft Kohle mbH (DE) | 2010-03-23 | — | — | US | disclosed |
| WO-2010003226-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | THADANI AVINASH N (CA) | 2010-01-14 | — | — | WO | disclosed |
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-11-12 | — | — | US | disclosed |
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-11-12 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| US-7479574-B2 | Method of producing macrocyclic ketone, and intermediate thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-01-20 | — | — | US | disclosed |
| WO-2008009275-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2008-01-24 | — | — | WO | disclosed |
| US-20070287870-A1 | Method of Producing Macrocyclic Ketone, and Intermediate Thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-13 | — | — | US | disclosed |
| EP-1845078-A1 | PROCESS FOR PRODUCING LARGE CYCLIC KETONE AND INTERMEDIATE THEREFOR | Takasago International Corporation (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287870-A1 | Method of Producing Macrocyclic Ketone, and Intermediate Thereof | MSMO1, CYP17A1, DNMT1 | MEN1 57/4885KMT2A 553/4885SLC18A3 598/4885 |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | ICMT, OTC, PNPO | MEN1 2400/4885KMT2A 2501/4885SLC18A3 1574/4885 |
| US-20110118475-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | AOC1, ODC1, AMD1 | MEN1 267/4885KMT2A 1109/4885SLC18A3 911/4885 |
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | AOC3, AOC2, AOC1 | MEN1 2676/4885KMT2A 4040/4885SLC18A3 3666/4885 |
| US-20130237583-A1 | PROCESS FOR THE PREPARATION OF DIHYDROPYRROLE DERIVATIVES | CYP1A1, CYP1B1, CYP1A2 | MEN1 1740/4885KMT2A 2160/4885SLC18A3 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.