SCHEMBL1763293

SCHEMBL1763293

c1ccc(C2CCC(c3ccccc3)N2)cc1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
SLC18A3 Q16572 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
PRCP P42785 1/20 0.45
KCNH2 Q12809 1/20 0.43
SCN3A Q9NY46 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
DPP4 P27487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23393883 1.00 MEN1 (0.50) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL1763291 1.00 MEN1 (0.50) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL13363848 1.00 MEN1 (0.50) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL1763221 1.00 MEN1 (0.50) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL13436114 1.00 MEN1 (0.50) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL14065400 0.90 MEN1 (0.47) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL4865057 0.90 MEN1 (0.47) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL6924404 0.90 MEN1 (0.47) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL11468464 0.87 MEN1 (0.45) MEN1KMT2ASLC18A3SIGMAR1PRCP
SCHEMBL19283462 0.86 MEN1 (0.64) MEN1KMT2APRCPKCNH2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032047-B Method for producing optically active compound 多特疗法-1公司 2023-10-27 CN claimed
US-7423059-B2 Pharmaceutically active compounds and methods of use WYETH (US) 2008-09-09 US claimed
WO-2025089237-A1 ADHESIVE COMPOSITION, CONNECTION STRUCTURE, AND METHOD FOR PRODUCING CONNECTION STRUCTURE 株式会社レゾナック 2025-05-01 WO disclosed
CN-117447464-A Method for producing optically active compound 首日生物制药公司 2024-01-26 CN disclosed
CN-111032047-B Method for producing optically active compound 多特疗法-1公司 2023-10-27 CN disclosed
US-20230121302-A1 METHODS OF IRON CATALYZED C-H BOND AMINATION VERSITECH LIMITED (CN) 2023-04-20 US disclosed
US-11561471-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-01-24 US disclosed
US-11543749-B2 Resist composition and method for producing resist pattern, and method for producing plated molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-01-03 US disclosed
US-20210278765-A1 RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN, AND METHOD FOR PRODUCING PLATED MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-09-09 US disclosed
US-10969685-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-06 US disclosed
CN-107001799-B Resin composition, solid-state imaging device using the same, and method for manufacturing the same 东丽株式会社 2020-11-27 CN disclosed
WO-2010003226-A1 CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS THADANI AVINASH N (CA) 2010-01-14 WO disclosed
US-7479574-B2 Method of producing macrocyclic ketone, and intermediate thereof TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-01-20 US disclosed
US-7423059-B2 Pharmaceutically active compounds and methods of use WYETH (US) 2008-09-09 US disclosed
US-20070287870-A1 Method of Producing Macrocyclic Ketone, and Intermediate Thereof TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-12-13 US disclosed
EP-1845078-A1 PROCESS FOR PRODUCING LARGE CYCLIC KETONE AND INTERMEDIATE THEREFOR Takasago International Corporation (JP) 2007-10-17 EP disclosed
EP-0930312-B1 Production method of optically active amino alcohols JAPAN TOBACCO INC (JP) 2003-01-02 EP disclosed
US-6197966-B1 REACTING MESOEPOXIDE WITH AMINE TO FORM 1,3-DIOXEPANE DERIVATIVE; ACID CATALYSIS; RING CONTRACTION TO 1,3-DIOXOLANE JAPAN TOBACCO INC. (JP) 2001-03-06 US disclosed
EP-0930312-A1 Production method of optically active amino alcohols Japan Tobacco Inc. (JP) 1999-07-21 EP disclosed
US-5610144-A CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS RHONE-POULENC RORER S.A. (FR) 1997-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070287870-A1 Method of Producing Macrocyclic Ketone, and Intermediate Thereof MSMO1, CYP17A1, DNMT1 MEN1 57/4885KMT2A 553/4885SLC18A3 598/4885
US-20230121302-A1 METHODS OF IRON CATALYZED C-H BOND AMINATION FTH1, FECH, HCCS MEN1 2070/4885KMT2A 624/4885SLC18A3 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.