Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 6/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924480 | 1.00 | PRKCB (0.46) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL16111150 | 0.77 | PHGDH (0.45) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14860965 | 0.77 | HRH3 (0.61) | ROCK2ROCK1PHGDH | |
| SCHEMBL14146963 | 0.76 | PRKCQ (0.59) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL5802241 | 0.76 | KDM4E (0.48) | CYP2C19PHGDH | |
| SCHEMBL13354904 | 0.75 | ROCK2 (0.50) | PIM1PIM3PIM2ROCK2ROCK1 | |
| SCHEMBL14216367 | 0.75 | ROCK2 (0.50) | PIM1PIM3PIM2ROCK2ROCK1 | |
| SCHEMBL14216365 | 0.75 | ROCK2 (0.50) | PIM1PIM3PIM2ROCK2ROCK1 | |
| SCHEMBL14193581 | 0.75 | ROCK2 (0.57) | ROCK2ROCK1CCR2HTT | |
| SCHEMBL14193590 | 0.75 | ROCK2 (0.57) | ROCK2ROCK1CCR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024710-A1 | UREA COMPOUNDS ACTIVE AS VANILLOID RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2004-03-25 | — | — | WO | disclosed |