Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.61 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212615 | 0.98 | LTA4H (0.63) | LTA4HKCNA3CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL425903 | 0.98 | LTA4H (0.63) | LTA4HKCNA3CYP2D6CYP1A2CYP19A1 | |
| Bromide SCHEMBL3130299 | 0.96 | LTA4H (0.61) | LTA4HKCNA3CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL482305 | 0.93 | LTA4H (0.64) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL9333524 | 0.93 | LTA4H (0.64) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL2437395 | 0.93 | LTA4H (0.64) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL482139 | 0.93 | LTA4H (0.64) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL482308 | 0.93 | LTA4H (0.64) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| Ethane SCHEMBL2441158 | 0.91 | LTA4H (0.62) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| Methane SCHEMBL2436452 | 0.91 | LTA4H (0.62) | LTA4HKCNA3MLNRNR1I2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158363-B1 | Positive resist composition and onium salts of saccharin derivatives | FUJIFILM CORP (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-6605409-B2 | Includes a compound that generates a specific sulfonimide compound by irradiation with an actinic ray or a radiation and (B) a resin having an acid decomposable group which increases solubility in an alkali developer; improved resolving power | FUJI PHOTO FILM CO., LTD. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020006578-A1 | Positive resist composition | FUJI PHOTO FILM CO., LTD. | 2002-01-17 | — | — | US | disclosed |
| EP-1158363-A1 | Positive resist composition and onium salts of saccharin derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |