Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922477 | 0.81 | GAA (0.35) | DPP4PIM1GAAPARP14 | |
| SCHEMBL6924489 | 0.76 | ABCC1 (0.41) | ABCC1DPP4PIM1CDK9 | |
| SCHEMBL6924927 | 0.69 | ABCC1 (0.48) | ABCC1PIM1CDK9 | |
| SCHEMBL21072543 | 0.66 | PARP1 (0.42) | PARP14PARP10PARP11 | |
| SCHEMBL30160008 | 0.66 | PARP1 (0.42) | PARP14PARP10PARP11 | |
| SCHEMBL6923754 | 0.65 | ABCC1 (0.43) | ABCC1GAA | |
| SCHEMBL21071874 | 0.63 | SMN1; SMN2 (0.42) | PARP14PARP10PARP11 | |
| SCHEMBL21072812 | 0.62 | PARP14 (0.46) | PARP14PARP10PARP11 | |
| SCHEMBL15549543 | 0.62 | PDE10A (0.49) | — | |
| SCHEMBL11803526 | 0.61 | PDE5A (0.49) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111052-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE (MDR) | XENOVA LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |