SCHEMBL692484

SCHEMBL692484

Brc1ccc2ccncc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.52
CYP11B2 P19099 1/20 0.52
PRKCZ Q05513 1/20 0.50
CYP2A6 P11509 1/20 0.50
CDK9 P50750 2/20 0.44
CCNT1 O60563 1/20 0.44
PIM1 P11309 1/20 0.44
HASPIN Q8TF76 1/20 0.44
MELK Q14680 1/20 0.44
GSK3A P49840 1/20 0.44
CDK5 Q00535 1/20 0.44
TAOK1 Q7L7X3 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
CHUK O15111 1/20 0.43
IMPDH2 P12268 1/20 0.42
CYP19A1 P11511 1/20 0.42
TBXAS1 P24557 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30368907 1.00 CYP11B1 (0.52) CYP11B1CYP11B2PRKCZCYP2A6CDK9
SCHEMBL31595960 0.98 CYP11B1 (0.50) CYP11B1CYP11B2PRKCZCYP2A6CDK9
Hydrochloric Acid SCHEMBL2241644 0.98 CYP11B1 (0.50) CYP11B1CYP11B2PRKCZCYP2A6CDK9
SCHEMBL29547785 0.91 CYP11B1 (0.56) CYP11B1CYP11B2PRKCZCYP2A6CDK9
SCHEMBL484716 0.91 CYP11B1 (0.56) CYP11B1CYP11B2PRKCZCYP2A6CDK9
Ammonia Solution, Strong SCHEMBL27725592 0.89 CYP11B1 (0.55) CYP11B1CYP11B2PRKCZCYP2A6CDK9
Water SCHEMBL28177305 0.89 CYP11B1 (0.55) CYP11B1CYP11B2PRKCZCYP2A6CDK9
Biphenyl SCHEMBL27880420 0.81 CYP11B1 (0.60) CYP11B1CYP11B2PRKCZCYP2A6CDK9
Formic Acid SCHEMBL28223024 0.81 CYP11B1 (0.47) CYP11B1CYP11B2CYP2A6CDK9CCNT1
SCHEMBL28455526 0.79 HIPK2 (0.53) CYP11B1CYP11B2CYP2A6CDK9GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800909-A Synthetic method of nitrogen-containing aromatic heterocyclic methylamine 北京六合宁远医药科技股份有限公司 2024-04-02 CN claimed
CN-113200941-B Column aromatic hydrocarbon fluorescent adsorption material containing phenothiazine and preparation method thereof 华东理工大学 2022-08-26 CN claimed
CN-113200941-A Column aromatic hydrocarbon fluorescent adsorption material containing phenothiazine and preparation method thereof 华东理工大学 2021-08-03 CN claimed
US-20260137677-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 TOCRIS COOKSON LTD (GB) 2026-05-21 US disclosed
CN-122036558-A Gossypol derivative, preparation method thereof and application thereof in preparation of coronavirus 3CL protease inhibitor 陕西盘龙药业集团股份有限公司 2026-05-15 CN disclosed
US-12552830-B2 Steroidal compound derivatives as therapeutic agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-02-17 US disclosed
CN-121108048-A Synthesis method of 7-aminoisoquinoline 上海毕得医药科技股份有限公司 2025-12-12 CN disclosed
EP-4079724-B1 2-(2-CHLOROPHENYL)-N-(5-SULFAMOYLISOQUINOLIN-7-YL)ACETAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS P2X4 ANTAGONISTS FOR THE TREATMENT OF E.G. URINARY TRACT DISEASES WUHAN LL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD (CN) 2025-11-12 EP disclosed
US-12441708-B2 Cereblon ligands and bifunctional compounds comprising the same ARVINAS OPERATIONS, INC. (US) 2025-10-14 US disclosed
US-20250313547-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME ARVINAS OPERATIONS INC (US) 2025-10-09 US disclosed
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-10-07 US disclosed
CN-1275979-A Isoquinoline compounds useful as urokinase inhibitors PFIZER (US) 2000-12-06 CN disclosed
WO-2000071512-A1 INHIBITORS OF FACTOR Xa COR THERAPEUTICS, INC. (US) 2000-11-30 WO disclosed
WO-2000047554-A2 INHIBITORS OF FACTOR Xa COR THERAPEUTICS INC. (US) 2000-08-17 WO disclosed
EP-1023268-A1 ISOQUINOLINES AS UROKINASE INHIBITORS Pfizer Limited (GB) 2000-08-02 EP disclosed
EP-0975600-A1 HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS Akzo Nobel N.V. (NL) 2000-02-02 EP disclosed
WO-1999020608-A1 ISOQUINOLINES AS UROKINASE INHIBITORS PFIZER LIMITED (GB) 1999-04-29 WO disclosed
WO-1998047876-A1 HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS AKZO NOBEL N.V. (NL) 1998-10-29 WO disclosed
EP-0632808-A1 ANTIVIRAL PEPTIDES Pfizer Limited (GB) 1995-01-11 EP disclosed
WO-1993019059-A1 ANTIVIRAL PEPTIDES PFIZER LIMITED (GB) 1993-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313547-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME CRBN, CBL, MDM2 CYP11B1 4434/4885CYP11B2 4416/4885PRKCZ 1206/4885
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 INMT, CARM1, KDM1B CYP11B1 2100/4885CYP11B2 2623/4885PRKCZ 4190/4885
US-20260137677-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 XIAP, MDM2, SARS1 CYP11B1 4443/4885CYP11B2 4376/4885PRKCZ 773/4885
US-12552830-B2 Steroidal compound derivatives as therapeutic agents PGF, NR3C2, NR5A1 CYP11B1 5/4885CYP11B2 19/4885PRKCZ 3072/4885
US-12441708-B2 Cereblon ligands and bifunctional compounds comprising the same CRBN, CBL, MDM2 CYP11B1 4434/4885CYP11B2 4416/4885PRKCZ 1206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.