Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.60 |
| ▸ | F10 | P00742 | 9/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.60 |
| ▸ | F12 | P00748 | 7/20 | 0.57 |
| ▸ | F7 | P08709 | 7/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | F9 | P00740 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9551619 | 0.82 | ACE (0.47) | ELANE | |
| Trifluoroacetic Acid SCHEMBL7447612 | 0.76 | F2 (0.49) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL3472243 | 0.75 | ACE (0.60) | F2 | |
| Trifluoroacetic Acid SCHEMBL17222079 | 0.74 | F2 (0.82) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL17222114 | 0.73 | F2 (0.90) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7449971 | 0.73 | F2 (0.48) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL16426767 | 0.72 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7443905 | 0.72 | F2 (0.49) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7452129 | 0.72 | F2 (0.49) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL12968999 | 0.71 | F2 (0.70) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515011-B2 | Anticoagulants | MERCK & CO., INC. | 2003-02-04 | — | — | US | disclosed |
| US-20020119992-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119992-A1 | Thrombin inhibitors | SERPINC1, F2, TFPI | F2 2/4885F10 22/4885PRSS1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.