Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472243 | 0.83 | ACE (0.60) | ACELMNA | |
| Trifluoroacetic Acid SCHEMBL6925100 | 0.82 | F2 (0.60) | ELANE | |
| SCHEMBL7943694 | 0.81 | ELANE (0.46) | ACEELANEDPP4ERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL26616483 | 0.78 | DPP4 (0.49) | ACEDPP4DPP8ERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL31376322 | 0.78 | DPP4 (0.49) | ACEDPP4DPP8ERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL9551620 | 0.77 | DPP4 (0.61) | ACEDPP4DPP8FAP | |
| Trifluoroacetic Acid SCHEMBL6567389 | 0.77 | CTSL (0.43) | DPP4DPP8LMNAHTT | |
| SCHEMBL15727160 | 0.77 | PREP (0.44) | ACEELANELMNAPREPFAP | |
| SCHEMBL26616424 | 0.77 | PREP (0.67) | ACEDPP4DPP8PREPFAP | |
| SCHEMBL26616429 | 0.77 | PREP (0.67) | ACEDPP4DPP8PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212158-A | Nootropic agents | INORGAN SA RECHERCHE & DEVELOPPEMENT PHARMACEUTIQUES, CAS (CH) | 1993-05-18 | — | — | US | disclosed |