Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10198708 | 0.87 | BTK (0.57) | BTKMAP3K7TAB1HTR2CHRH3 | |
| SCHEMBL10260771 | 0.76 | BTK (0.60) | BTKMAP3K7TAB1HTR2CHRH3 | |
| SCHEMBL21105139 | 0.69 | HTR2C (0.42) | MAP3K7TAB1HTR2CHRH3TGFBR1 | |
| SCHEMBL16154952 | 0.65 | HTR2C (0.56) | HTR2CSIGMAR1KDM4EALDH1A1MAPT | |
| SCHEMBL20200674 | 0.65 | HTR2C (0.49) | HTR2CHRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL24736691 | 0.62 | SIGMAR1 (0.49) | HTR2CHRH3TGFBR1ACVR1KCNH2 | |
| SCHEMBL20847736 | 0.61 | HTR2C (0.50) | HTR2CSIGMAR1KDM4EALDH1A1MAPT | |
| SCHEMBL15001446 | 0.59 | HRH3 (0.46) | HTR2CHRH3TGFBR1ACVR1KCNH2 | |
| Hydrochloric Acid SCHEMBL9531906 | 0.59 | HTR2C (0.43) | HTR2CSIGMAR1KDM4EALDH1A1MAPT | |
| SCHEMBL15001490 | 0.59 | HRH3 (0.42) | HTR2CHRH3TGFBR1ACVR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119663-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |