SCHEMBL6925319

SCHEMBL6925319

CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)ccc2c1OC(C(=O)NC(CC)C(NC(=O)OC(C)(C)C)C(=O)O)CC2

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.69
LTB4R2 Q9NPC1 13/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110359 0.91 LTB4R (0.57) LTB4RLTB4R2
SCHEMBL6756216 0.87 LTB4R (0.67) LTB4RLTB4R2
SCHEMBL6756221 0.86 LTB4R (0.67) LTB4RLTB4R2
SCHEMBL6920861 0.85 LTB4R (0.66) LTB4RLTB4R2
SCHEMBL6756217 0.84 LTB4R (0.67) LTB4RLTB4R2
SCHEMBL3679470 0.82 LTB4R (1.00) LTB4RLTB4R2
SCHEMBL6756223 0.82 LTB4R (0.67) LTB4RLTB4R2
SCHEMBL6759812 0.82 LTB4R (0.75) LTB4RLTB4R2
SCHEMBL6756168 0.81 LTB4R (0.74) LTB4RLTB4R2
SCHEMBL6965405 0.81 LTB4R (0.76) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099810-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2003-12-04 WO disclosed
EP-1347784-A2 SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION Bristol-Myers Squibb Pharma Company (US) 2003-10-01 EP disclosed
WO-2002036173-A2 SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-05-10 WO disclosed