Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | PDE6D | O43924 | 3/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6923145 | 0.99 | NPY1R (0.43) | NPY1RACP1PDE6DHTR4MERTK | |
| SCHEMBL6922923 | 0.94 | NPY1R (0.41) | NPY1RACP1PDE6DHTR4MERTK | |
| SCHEMBL6929551 | 0.93 | PDE6D (0.41) | NPY1RACP1PDE6DHTR4MAOB | |
| Fumaric Acid SCHEMBL729085 | 0.92 | HDAC1 (0.41) | NPY1RACP1PDE6DHTR4MERTK | |
| Fumaric Acid SCHEMBL729086 | 0.92 | HDAC1 (0.41) | NPY1RACP1PDE6DHTR4MERTK | |
| SCHEMBL6929042 | 0.91 | NPY1R (0.40) | NPY1RACP1PDE6DHTR4MAOB | |
| SCHEMBL6923151 | 0.91 | ACP1 (0.47) | NPY1RACP1PDE6DHTR4ALDH1A1 | |
| SCHEMBL6930321 | 0.90 | NPY1R (0.43) | NPY1RACP1PDE6DMERTKMAOB | |
| SCHEMBL6927586 | 0.89 | NPY1R (0.39) | NPY1RACP1PDE6DHTR4MERTK | |
| SCHEMBL27570136 | 0.89 | ACP1 (0.40) | NPY1RACP1PDE6DHTR4AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | claimed |
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |