SCHEMBL6927586

SCHEMBL6927586

Cc1ccc2nc(Cl)c3nc(-c4ccccc4)n(CCC4CCNCC4)c3c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 1/20 0.39
MERTK Q12866 1/20 0.38
AVPR2 P30518 3/20 0.37
AVPR1A P37288 3/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
TRIM58 Q8NG06 3/20 0.36
ACP1 P24666 2/20 0.36
PDE6D O43924 2/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
KHK P50053 2/20 0.36
NLRP3 Q96P20 1/20 0.35
RAB9A P51151 1/20 0.35
PIM1 P11309 1/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
HTR4 Q13639 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6930321 0.91 NPY1R (0.43) NPY1RMERTKAVPR2AVPR1AKDM4E
SCHEMBL6922923 0.89 NPY1R (0.41) NPY1RMERTKAVPR2AVPR1AALDH1A1
SCHEMBL6925914 0.89 NPY1R (0.44) NPY1RMERTKAVPR2AVPR1AALDH1A1
SCHEMBL6928523 0.89 NPY1R (0.42) NPY1RAVPR2AVPR1AALDH1A1LMNA
Hydrochloric Acid SCHEMBL6923145 0.88 NPY1R (0.43) NPY1RMERTKAVPR2AVPR1AACP1
SCHEMBL6838674 0.87 ADRB2 (0.39) NPY1RMERTKAVPR2AVPR1ALMNA
SCHEMBL6927830 0.85 ADRB2 (0.40) NPY1RKHKPIM1PIM3PIM2
SCHEMBL6929551 0.83 PDE6D (0.41) NPY1RAVPR2AVPR1AKDM4EALDH1A1
SCHEMBL6923151 0.82 ACP1 (0.47) NPY1RKDM4EALDH1A1LMNAMAPT
SCHEMBL6926458 0.82 NPY1R (0.41) NPY1RMERTKAVPR2AVPR1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed