SCHEMBL6922923

SCHEMBL6922923

Cc1ccc(-c2nc3c(Cl)nc4ccccc4c3n2CCC2CCNCC2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HTR4 Q13639 1/20 0.39
PDE6D O43924 1/20 0.38
AVPR2 P30518 3/20 0.38
AVPR1A P37288 3/20 0.38
RXFP1 Q9HBX9 2/20 0.38
ACP1 P24666 4/20 0.37
ABCC1 P33527 1/20 0.37
MERTK Q12866 1/20 0.36
KDM1A O60341 1/20 0.36
MAOB P27338 1/20 0.36
HTR6 P50406 1/20 0.36
PTGER4 P35408 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6925914 0.94 NPY1R (0.44) NPY1RALDH1A1HTR4PDE6DAVPR2
Hydrochloric Acid SCHEMBL6923145 0.93 NPY1R (0.43) NPY1RHTR4PDE6DAVPR2AVPR1A
SCHEMBL6929551 0.91 PDE6D (0.41) NPY1RALDH1A1HTR4PDE6DAVPR2
SCHEMBL6923151 0.91 ACP1 (0.47) NPY1RMEN1KMT2AALDH1A1HTR4
SCHEMBL6929042 0.90 NPY1R (0.40) NPY1RMEN1KMT2AHTR4PDE6D
SCHEMBL6927586 0.89 NPY1R (0.39) NPY1RALDH1A1HTR4PDE6DAVPR2
SCHEMBL27570136 0.89 ACP1 (0.40) NPY1RHTR4PDE6DAVPR2AVPR1A
SCHEMBL6840049 0.87 ALDH1A1 (0.38) NPY1RMEN1KMT2AALDH1A1HTR4
Fumaric Acid SCHEMBL729085 0.86 HDAC1 (0.41) NPY1RALDH1A1HTR4PDE6DACP1
Fumaric Acid SCHEMBL729086 0.86 HDAC1 (0.41) NPY1RALDH1A1HTR4PDE6DACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed