Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968568 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL6121092 | 0.92 | ALDH1A1 (0.44) | HRH3BTKALDH1A1KMT2AMEN1 | |
| SCHEMBL21159154 | 0.92 | ALDH1A1 (0.44) | HRH3BTKALDH1A1KMT2AMEN1 | |
| SCHEMBL18435732 | 0.91 | BTK (0.41) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL23925520 | 0.90 | BTK (0.40) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL18906437 | 0.90 | CHRM2 (0.37) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL16077468 | 0.86 | NR1H2 (0.36) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL2450476 | 0.85 | BTK (0.44) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL14387419 | 0.85 | CHRM2 (0.34) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL2303235 | 0.83 | BTK (0.38) | CHRM2CHRM1CHRM3PREPNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515165-B1 | In a process of the present invention for producing a bridged cyclic polycarboxylic acid t-butyl ester, a bridged cyclic polycarboxylic halide of following Formula to react with a halogenating agent. an adsorption treatment step of subjecting | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| EP-1148043-A1 | PROCESS FOR PRODUCING t-BUTYL ESTERS OF BRIDGED-RING POLYCARBOXYLIC ACIDS | Daicel Chemical Industries, Ltd. (JP) | 2001-10-24 | — | — | EP | disclosed |