Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.64 |
| ▸ | HTR1A | P08908 | 12/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.64 |
| ▸ | HTR2C | P28335 | 5/20 | 0.64 |
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | HTR1B | P28222 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827483 | 0.92 | SLC6A2 (0.62) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL14549488 | 0.89 | HTR1D (0.61) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL5669748 | 0.87 | SLC6A2 (0.68) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL23228665 | 0.86 | HTR2C (0.67) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL15473204 | 0.85 | HTR1D (0.67) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL23228751 | 0.85 | HTR2C (0.65) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL4142513 | 0.84 | HTR1A (0.59) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL23228697 | 0.82 | SLC6A2 (0.58) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL23228623 | 0.82 | SLC6A2 (0.61) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL23228766 | 0.81 | SLC6A2 (0.59) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030120070-A1 | Serotonin 5-HT1A and dopamin D2 receptor ligands | H. LUNDBECK A/S (DE) | 2003-06-26 | — | — | US | disclosed |
| US-6514993-B1 | Useful in the treatment of certain psychic and neurologic disorders | H. LUNDBECK A/S (DK) | 2003-02-04 | — | — | US | disclosed |
| EP-0770066-B1 | SEROTONIN 5-HT 1A AND DOPAMIN D2 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2000-05-17 | — | — | EP | disclosed |
| EP-0770066-A1 | SEROTONIN 5-HT 1A AND DOPAMIN D2 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 1997-05-02 | — | — | EP | disclosed |
| WO-1995033729-A1 | SEROTONIN 5-HT1A AND DOPAMIN D2 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 1995-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120070-A1 | Serotonin 5-HT1A and dopamin D2 receptor ligands | HTR5A, HTR2C, HTR1D | SLC6A2 136/4885SLC6A4 138/4885HTR1A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.