Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.58 |
| ▸ | RXRB | P28702 | 11/20 | 0.57 |
| ▸ | RXRG | P48443 | 9/20 | 0.57 |
| ▸ | RARA | P10276 | 5/20 | 0.57 |
| ▸ | RARB | P10826 | 5/20 | 0.57 |
| ▸ | RARG | P13631 | 5/20 | 0.57 |
| ▸ | HNF4A | P41235 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029044 | 0.83 | RXRA (0.56) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7128382 | 0.83 | RXRA (0.54) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6925478 | 0.78 | RXRA (0.66) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8704549 | 0.76 | RXRA (0.71) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7023941 | 0.75 | RXRA (0.57) | RXRARXRBRXRGRARARARB | |
| SCHEMBL23393319 | 0.75 | RAB9A (0.55) | — | |
| SCHEMBL21486409 | 0.75 | RAB9A (0.55) | — | |
| SCHEMBL4423837 | 0.73 | RXRA (0.62) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8776401 | 0.73 | RXRA (0.54) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7135063 | 0.73 | RXRA (0.54) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515021-B1 | Bicyclic aromatic compounds | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2003-02-04 | — | — | US | disclosed |