Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927698 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6923907 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6930115 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27570174 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6927398 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6927222 | 0.74 | ACKR3 (0.45) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6928651 | 0.72 | SLC6A2 (0.39) | ALDH1A1TSHRSMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL10743391 | 0.70 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL6925914 | 0.70 | NPY1R (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10739020 | 0.70 | TLR7 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |