Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758125 | 0.74 | CYP1A2 (0.33) | GABRA5GABRB2GABRA1GABRA4ALDH1A1 | |
| SCHEMBL31555107 | 0.64 | AKR1B1 (0.35) | GABRA5GABRB2GABRA1GABRA4AKR1B1 | |
| SCHEMBL10768267 | 0.63 | GABRA5 (0.31) | GABRA5GABRB2GABRA1GABRA4AKR1B1 | |
| SCHEMBL7122558 | 0.61 | CYP1A2 (0.67) | GABRA5GABRB2GABRA1GABRA4ALDH1A1 | |
| SCHEMBL6596474 | 0.59 | — | — | |
| SCHEMBL4649674 | 0.59 | — | — | |
| SCHEMBL874090 | 0.59 | CYP1A2 (0.50) | GABRA5GABRB2GABRA1GABRA4ALDH1A1 | |
| SCHEMBL31555065 | 0.58 | AKR1B1 (0.34) | GABRA5GABRB2GABRA1GABRA4AKR1B1 | |
| SCHEMBL23829540 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL6645397 | 0.57 | KDM4E (0.48) | GABRA5GABRB2GABRA1GABRA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |