Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6645397 | 0.97 | KDM4E (0.48) | CYP1A2KDM4EMAPTAKR1B1NAPRT | |
| Furan SCHEMBL473513 | 0.87 | CYP1A2 (0.42) | CYP1A2KDM4EMAPTAKR1B1NAPRT | |
| SCHEMBL5094342 | 0.81 | P2RX7 (0.41) | CYP1A2KDM4EMAPTNAPRTLMNA | |
| Butyl Alcohol SCHEMBL27561770 | 0.81 | ALDH1A1 (0.40) | CYP1A2KDM4EMAPTALDH1A1HTT | |
| SCHEMBL473621 | 0.77 | CYP1A2 (0.35) | CYP1A2KDM4EMAPTAKR1B1NAPRT | |
| SCHEMBL7769482 | 0.77 | P2RX7 (0.38) | CYP1A2KDM4EMAPTNAPRTLMNA | |
| SCHEMBL77616 | 0.77 | HTT (0.48) | CYP1A2KDM4EMAPTP2RX7HTT | |
| SCHEMBL6428658 | 0.77 | CYP1A2 (0.43) | CYP1A2KDM4EMAPTAKR1B1NAPRT | |
| SCHEMBL1719924 | 0.77 | LMNA (0.47) | CYP1A2KDM4EMAPTNAPRTLMNA | |
| SCHEMBL8539040 | 0.77 | P2RX7 (0.38) | CYP1A2KDM4EMAPTNAPRTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117904242-B | Sheep embryo extract polypeptide in Hu sheep body and application thereof in regulating immune function | 蚌埠学院 | 2025-02-25 | — | — | CN | claimed |
| US-20070129355-A1 | G-protein-coupled chemoattractant receptor, expressed on T helper cells antagonists such as [4-(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)-5-pyrimidinyl]acetic acid;, used for the treatment of allergic diseases, inflammatory diseases, eosinophil- and basophil-related diseases | ACTIMIS PHARMACEUTICALS, INC. (US) | 2007-06-07 | — | — | US | claimed |
| WO-2006100552-A1 | PROCESSES FOR THE PREPARATION OF LOPINAVIR AND ITS INTERMEDIATE - (S)-TETRAHYDRO-ALPHA-(1-METHYLETHYL)-2-OXO-1(2H)-PYRIMIDINEACETIC ACID | RANBAXY LABORATORIES LIMITED (IN) | 2006-09-28 | — | — | WO | claimed |
| EP-1471057-B1 | Pyrimidinylacetic acid derivatives useful for the treatment of diseases mediated by CRTH2 | ACTIMIS PHARMACEUTICALS INC (US) | 2006-01-18 | — | — | EP | claimed |
| EP-1471057-A1 | Pyrimidinylacetic acid derivatives useful for the treatment of diseases mediated by CRTH2 | Bayer HealthCare AG (DE) | 2004-10-27 | — | — | EP | claimed |
| CN-1407985-A | Heterocyclic dihydropyrimidines as potassium channel inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2003-04-02 | — | — | CN | claimed |
| US-5238907-A | Substituted 2-pyrimidinyl-acetic acid derivatives, and their use as herbicides, fungicides and plant growth regulators | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | claimed |
| EP-4029868-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2026-05-20 | — | — | EP | disclosed |
| US-12565498-B2 | β-lactamase inhibitors and their preparation | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2026-03-03 | — | — | US | disclosed |
| CN-120137642-A | Composite material, preparation method of film, photoelectric device and display equipment | 广东聚华新型显示研究院 | 2025-06-13 | — | — | CN | disclosed |
| US-20250188032-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | BNH RESEARCH CO., LTD. (KR) | 2025-06-12 | — | — | US | disclosed |
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| EP-4501910-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | BNH Research Co., Ltd. (KR) | 2025-02-05 | — | — | EP | disclosed |
| WO-1994022854-A1 | HERBICIDAL 1,4-DI-HETEROARYL PYRAZOLIDIN-3,5-DIONES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-10-13 | — | — | WO | disclosed |
| US-5238907-A | Substituted 2-pyrimidinyl-acetic acid derivatives, and their use as herbicides, fungicides and plant growth regulators | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| US-5006433-A | Printing plate precursors for electrophotographic plate-making purposes | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0048954-B1 | BETA-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | disclosed |
| EP-0048954-A2 | Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-04-07 | — | — | EP | disclosed |
| US-3929789-A | Pyrimidinyl acetic acid derivatives and processes for their production | ICI LTD | 1975-12-30 | — | — | US | disclosed |
| US-3929789-A | Pyrimidinyl acetic acid derivatives and processes for their production | ICI LTD | 1975-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129355-A1 | G-protein-coupled chemoattractant receptor, expressed on T helper cells antagonists such as [4-(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)-5-pyrimidinyl]acetic acid;, used for the treatment of allergic diseases, inflammatory diseases, eosinophil- and basophil-related diseases | HRH2, HRH1, HRH4 | CYP1A2 2709/4885KDM4E 4588/4885MAPT 2008/4885 |
| US-12565498-B2 | β-lactamase inhibitors and their preparation | PGLS, MGAM, OSTC | CYP1A2 1896/4885KDM4E 2288/4885MAPT 4709/4885 |
| US-20250188032-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | NLN, GRIN1, GRIN2A | CYP1A2 3411/4885KDM4E 938/4885MAPT 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.