Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27278524 | 0.83 | KLK7 (0.53) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5453827 | 0.83 | BCHE (0.51) | L3MBTL1ALDH1A1LMNARAB9AHDAC3 | |
| SCHEMBL1420885 | 0.81 | MEN1 (0.57) | KDM1AL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL19585161 | 0.81 | MEN1 (0.57) | KDM1AL3MBTL1MEN1KMT2AEPHX2 | |
| Bromide SCHEMBL10787284 | 0.81 | KDM1A (0.53) | KDM1AL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL11573347 | 0.80 | TERT (0.58) | KDM1AL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL3075021 | 0.79 | KDM1A (0.65) | KDM1AL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL11458040 | 0.79 | L3MBTL1 (0.66) | KDM1AL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL6018459 | 0.78 | NAPRT (0.61) | L3MBTL1MEN1KMT2AEPHX2MAPT | |
| SCHEMBL14520322 | 0.78 | HTT (0.43) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140803-B1 | ((AMINOIMINOMETHYL) AMINO) ALKANECARBOXAMIDES AND THEIR APPLICATIONS IN THERAPY | MERCK PATENT GMBH (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-6518458-B1 | ((aminoiminomethyl)amino)alkane-carboxamide type in the treatment of pathologies associated with insulin resistance syndrome. | MERCK PATENT GMBH (DE) | 2003-02-11 | — | — | US | disclosed |
| EP-1140803-A1 | ((AMINOIMINOMETHYL) AMINO) ALKANECARBOXAMIDES AND THEIR APPLICATIONS IN THERAPY | MERCK PATENT GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000042001-A1 | ((AMINOIMINOMETHYL) AMINO) ALKANECARBOXAMIDES AND THEIR APPLICATIONS IN THERAPY | MERCK PATENT GMBH (DE) | 2000-07-20 | — | — | WO | disclosed |