SCHEMBL6927504

SCHEMBL6927504

CC(CSCC(C)(c1ccccc1)c1cccc2ccccc12)(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.42
CYP2C19 P33261 5/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
CYP1A2 P05177 4/20 0.38
CYP2C9 P11712 2/20 0.38
HSD17B10 Q99714 3/20 0.36
CYP2D6 P10635 3/20 0.36
HPGD P15428 2/20 0.36
HIF1A Q16665 2/20 0.36
ACP3 P15309 2/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP2A6 P11509 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
TP53 P04637 1/20 0.33
ALOX15 P16050 1/20 0.33
CDC25B P30305 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5010153 0.81 CYP2C19 (0.41) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL5013836 0.79 CYP2C19 (0.39) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL5240009 0.79 CYP2C19 (0.42) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL3003485 0.74 CYP3A4 (0.42) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL5013862 0.74 TSHR (0.42) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL5008800 0.72 TSHR (0.40) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL9806370 0.72 CYP2C19 (0.56) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL19130800 0.72 CYP2C19 (0.56) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL7042389 0.72 KIF11 (0.42) KIF11CYP2C19CYP3A4TSHRCYP1A2
SCHEMBL6547270 0.71 ALDH1A1 (0.41) CYP2C19CYP3A4TSHRCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0846681-B1 NOVEL SULFONIUM SALT COMPOUNDS, POLYMERIZATION INITIATOR, CURABLE COMPOSITION, AND CURING METHOD NIPPON SODA CO (JP) 2003-12-03 EP disclosed
US-6093753-A CURABLE COMPOSITION COMPRISING A CATIONIC POLYMERIZABLE COMPOUND WHICH IS AN ALICYCLIC EPOXY COMPOUND OR A VINYL ETHER COMPOUND AND A CATIONIC POLYMERIZATION INITIATOR; PAINTS, ADHESIVES, INKS, PHOTORESISTS NIPPON SODA CO., LTD. (JP) 2000-07-25 US disclosed
EP-0846681-A1 NOVEL SULFONIUM SALT COMPOUNDS, POLYMERIZATION INITIATOR, CURABLE COMPOSITION, AND CURING METHOD NIPPON SODA CO., LTD. (JP) 1998-06-10 EP disclosed