Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.73 |
| ▸ | F10 | P00742 | 11/20 | 0.72 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.72 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.72 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.72 |
| ▸ | F12 | P00748 | 9/20 | 0.68 |
| ▸ | F7 | P08709 | 9/20 | 0.68 |
| ▸ | F9 | P00740 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17221964 | 0.84 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL17221962 | 0.84 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL20484185 | 0.84 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6921523 | 0.84 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL20567697 | 0.84 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL15298962 | 0.81 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6923431 | 0.81 | F2 (0.79) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6923426 | 0.78 | F2 (0.70) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6076705 | 0.78 | CYP3A4 (0.70) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL16426767 | 0.77 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857765-B1 | Stabilizing agents for powder paints | CIBA SC HOLDING AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| EP-0897958-B1 | Stabilisers for powder coatings | CIBA SC HOLDING AG (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6515011-B2 | Anticoagulants | MERCK & CO., INC. | 2003-02-04 | — | — | US | disclosed |
| US-20020119992-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2002-08-29 | — | — | US | disclosed |
| EP-0842975-B1 | Stabilising polyolefins for long term contact with an extracting medium | CIBA SC HOLDING AG (CH) | 2002-05-22 | — | — | EP | disclosed |
| EP-0839623-B1 | Stabiliser combination for rotomolding process | CIBA SC HOLDING AG (CH) | 2001-01-31 | — | — | EP | disclosed |
| EP-0591102-B1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000043459-A1 | CORROSION-INHIBITING COATING COMPOSITIONS FOR METALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-27 | — | — | WO | disclosed |
| EP-0648765-B1 | Process for the production of 3-arylbenzofuranones | CIBA SC HOLDING AG (CH) | 2000-07-12 | — | — | EP | disclosed |
| EP-0644190-B1 | Benzofuran-2-ones as stabilizers | CIBA GEIGY AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| EP-0857765-A2 | Stabilizing agents for powder paints | Ciba SC Holding AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| EP-0842975-A1 | Stabilising polyolefins for long term contact with an extracting medium | Ciba SC Holding AG (CH) | 1998-05-20 | — | — | EP | disclosed |
| EP-0839623-A1 | Stabiliser combination for rotomolding process | Ciba SC Holding AG (CH) | 1998-05-06 | — | — | EP | disclosed |
| EP-0707035-A1 | HALS phosphorinanes as stabilisers | CIBA-GEIGY AG (CH) | 1996-04-17 | — | — | EP | disclosed |
| EP-0685519-A1 | Oligomeric HALS-phosphites and HALS-phosphonites as stabilizers | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |
| EP-0648765-A1 | Process for the production of 3-arylbenzofuranones | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| EP-0644190-A1 | Benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1995-03-22 | — | — | EP | disclosed |
| EP-0608198-A1 | Cyclic diphenylacetonenitriles as stabilisers | CIBA-GEIGY AG (CH) | 1994-07-27 | — | — | EP | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |
| EP-0232224-B1 | PIPERIDINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119992-A1 | Thrombin inhibitors | SERPINC1, F2, TFPI | F2 2/4885F10 22/4885PRSS1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.