Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | IRS1 | P35568 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831410 | 0.96 | HSD11B1 (0.51) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL5832066 | 0.94 | HSD11B1 (0.50) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL7059008 | 0.88 | HSD11B1 (0.49) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL5830954 | 0.84 | HSD11B1 (0.52) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL5831177 | 0.83 | HSD11B1 (0.51) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL5831913 | 0.82 | HSD11B1 (0.51) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL5832085 | 0.81 | HSD11B1 (0.68) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL5397908 | 0.81 | ATM (0.59) | HSD11B1HSD17B1HSD17B2EDNRBEDNRA | |
| SCHEMBL5830997 | 0.81 | HSD11B1 (0.54) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 | |
| SCHEMBL5831034 | 0.80 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2HTTSLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113310-A1 | USE OF AN INHIBITOR OF 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPOUNDS FOR PROMOTING WOUND HEALING | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | disclosed |