Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.54 |
| ▸ | BCHE | P06276 | 5/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928704 | 0.83 | HTR1D (0.54) | HTR6CYP19A1MCL1PLA2G2AUTS2R | |
| SCHEMBL6926244 | 0.82 | KDM4E (0.47) | HTR6CYP19A1MCL1PLA2G2AUTS2R | |
| SCHEMBL6921596 | 0.82 | HTR1A (0.43) | HTR6BCHECYP19A1MCL1PLA2G2A | |
| SCHEMBL6927422 | 0.82 | CYP19A1 (0.44) | HTR6BCHECYP19A1MCL1PLA2G2A | |
| SCHEMBL6921216 | 0.82 | HTR1B (0.53) | HTR6BCHECYP19A1MCL1PLA2G2A | |
| SCHEMBL6925529 | 0.81 | HTR6 (0.47) | HTR6CYP19A1MCL1PLA2G2AUTS2R | |
| SCHEMBL6925119 | 0.81 | HTR1B (0.54) | HTR6CYP19A1MCL1PLA2G2AUTS2R | |
| SCHEMBL6921654 | 0.81 | HTR6 (0.49) | HTR6CYP19A1UTS2R | |
| SCHEMBL6926040 | 0.80 | HTR6 (0.47) | HTR6BCHECYP19A1MCL1PLA2G2A | |
| SCHEMBL6927462 | 0.79 | HTR6 (0.46) | HTR6CYP19A1MCL1PLA2G2AUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514968-B1 | Treating a disease or condition in a mammal wherein the 5-HT receptor is implicated and modulation of 5-HT function is desired comprising | PHARMACIA & UPJOHN COMPANY | 2003-02-04 | — | — | US | claimed |
| US-6514968-B1 | Treating a disease or condition in a mammal wherein the 5-HT receptor is implicated and modulation of 5-HT function is desired comprising | PHARMACIA & UPJOHN COMPANY | 2003-02-04 | — | — | US | disclosed |
| EP-1210329-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017963-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |