Dimethylformamide

Dimethylformamide

SCHEMBL6927882

CC(=O)OC(C)C.CN(C)C=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
HCAR2 Q8TDS4 1/20 0.37
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
GALR3 O60755 1/20 0.34
MAPT P10636 1/20 0.34
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28102305 0.82 TSHR (0.78) TSHRHCAR2CHRM2CHRM4CHRM1
SCHEMBL19193 0.82
SCHEMBL21064874 0.82 TSHR (1.00) TSHRHCAR2CHRM2CHRM4CHRM1
Formamide SCHEMBL8708733 0.80 TSHR (0.74) TSHRHCAR2CHRM2CHRM4CHRM1
SCHEMBL28276475 0.79 TSHR (0.82) TSHRHCAR2CHRM2CHRM4CHRM1
Methyl Alcohol SCHEMBL584909 0.79
Ammonia Solution, Strong SCHEMBL5086843 0.79
SCHEMBL4431010 0.79 TSHR (0.93) TSHRHCAR2CHRM2CHRM4CHRM1
SCHEMBL3495565 0.79
Hydrochloric Acid SCHEMBL2107550 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2956439-B1 PROCESS FOR PREPARING ATAZANAVIR SULPHATE CIPLA LTD (IN) 2019-01-09 EP claimed
US-9890121-B2 Process for preparing atazanavir sulphate CIPLA LIMITED (IN) 2018-02-13 US claimed
US-20160002166-A1 Process for Preparing Atazanavir Sulphate CIPLA LIMITED (IN) 2016-01-07 US claimed
EP-0915898-B1 CRYSTAL FORM I OF CLARITHROMYCIN ABBOTT LAB (US) 2003-12-03 EP claimed
US-5858986-A CONVERTING ERYTHROMYCIN A INTO ITS 9-OXIME DERIVATIVE; PROTECTING 2' AND 4? HYDROXY GROUPS; METHYLATION; DEPROTECTING AND DEOXIMATING; TREATING WITH SOLVENT; ISOLATION; DRYING ABBOTT LABORATORIES (US) 1999-01-12 US claimed
EP-2956439-B1 PROCESS FOR PREPARING ATAZANAVIR SULPHATE CIPLA LTD (IN) 2019-01-09 EP disclosed
CN-109071788-A Aliphatic polycarbonate resin, next door material, substrate and its manufacturing method, the manufacturing method of circuit board and Wiring method 住友精化株式会社 2018-12-21 CN disclosed
CN-108884372-A Pyrolytic adhesive 国立大学法人东京农工大学 2018-11-23 CN disclosed
CN-108884218-A Next door is formed with aliphatic polycarbonate resin, next door material, substrate and its manufacturing method, the manufacturing method of circuit board and Wiring method 住友精化株式会社 2018-11-23 CN disclosed
US-9890121-B2 Process for preparing atazanavir sulphate CIPLA LIMITED (IN) 2018-02-13 US disclosed
US-20160002166-A1 Process for Preparing Atazanavir Sulphate CIPLA LIMITED (IN) 2016-01-07 US disclosed
EP-2956439-A1 PROCESS FOR PREPARING ATAZANAVIR SULPHATE Cipla Limited (IN) 2015-12-23 EP disclosed
EP-2138871-B1 OPTICAL COMPENSATION LAYER, OPTICALLY COMPENSATING FILM, AND PROCESSES FOR PRODUCING THESE TOSOH CORP (JP) 2015-06-17 EP disclosed
WO-2014125270-A1 PROCESS FOR PREPARING ATAZANAVIR SULPHATE CIPLA HOUSE (IN) 2014-08-21 WO disclosed
EP-0915898-B1 CRYSTAL FORM I OF CLARITHROMYCIN ABBOTT LAB (US) 2003-12-03 EP disclosed
US-5858986-A CONVERTING ERYTHROMYCIN A INTO ITS 9-OXIME DERIVATIVE; PROTECTING 2' AND 4? HYDROXY GROUPS; METHYLATION; DEPROTECTING AND DEOXIMATING; TREATING WITH SOLVENT; ISOLATION; DRYING ABBOTT LABORATORIES (US) 1999-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002166-A1 Process for Preparing Atazanavir Sulphate SAMHD1, TPMT, ASH2L TSHR 4428/4885HCAR2 4524/4885CHRM2 3793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.