Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107952 | 0.87 | EPHX1 (0.58) | CTNNB1ALDH1A1TDP1MMP9MMP8 | |
| SCHEMBL7272663 | 0.82 | CTNNB1 (0.75) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL9518880 | 0.81 | ALDH1A1 (0.50) | CTNNB1ALDH1A1TDP1SLC1A3SLC1A2 | |
| SCHEMBL6677809 | 0.81 | CTNNB1 (0.63) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL8871925 | 0.81 | CTNNB1 (0.59) | CTNNB1ALDH1A1TDP1MMP9MMP8 | |
| SCHEMBL5831545 | 0.80 | TDP1 (0.50) | CTNNB1TDP1MMP9MMP8MMP14 | |
| SCHEMBL599243 | 0.80 | ALDH1A1 (0.51) | CTNNB1ALDH1A1TDP1CYP2C19 | |
| SCHEMBL2684738 | 0.79 | CTNNB1 (0.61) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL1826710 | 0.79 | CTNNB1 (0.61) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10170673 | 0.79 | CTNNB1 (0.61) | CTNNB1TDP1HRH4SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709082-A | 2-phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1987-11-24 | — | — | US | claimed |
| CN-1241913-C | Method of preparing 2-phenyl-3-naphthyl propionic acid derivative | DAIICHI SEIYAKU CO (JP) | 2006-02-15 | — | — | CN | disclosed |
| CN-1535955-A | Method of preparing 2-phenyl-3-naphthyl propionic acid derivative | 第一制药株式会社 | 2004-10-13 | — | — | CN | disclosed |
| CN-1535954-A | Method of preparing 2-phenyl-3-naphthyl propionic acid derivative | 第一制药株式会社 | 2004-10-13 | — | — | CN | disclosed |
| CN-1104415-C | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI SEIYAKU CO (JP) | 2003-04-02 | — | — | CN | disclosed |
| US-6515142-B2 | Intermediates of aromatic amidine derivatives which have anticoagulation action | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6515142-B2 | Intermediates of aromatic amidine derivatives which have anticoagulation action | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-6337405-B1 | MULTISTAGE REACTION OF PYRROLE SUBSTITUTED WITH SULFONATE GROUPS AND HYDROXYPHENYLACETIC ACID | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6337405-B1 | MULTISTAGE REACTION OF PYRROLE SUBSTITUTED WITH SULFONATE GROUPS AND HYDROXYPHENYLACETIC ACID | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6252088-B1 | COUPLING A NITRILE CONTAININ NAPHTHALENE COMPOUND WITH A COMPOUND CONTAINING PROPIONIC ACID GROUP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| US-6252088-B1 | COUPLING A NITRILE CONTAININ NAPHTHALENE COMPOUND WITH A COMPOUND CONTAINING PROPIONIC ACID GROUP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| CN-1232449-A | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI SEIYAKU CO (JP) | 1999-10-20 | — | — | CN | disclosed |
| EP-0936215-A1 | PROCESS FOR PREPARING 2-PHENYL-3-NAPHTHYLPROPIONIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |
| EP-0179487-B1 | 2-PHENYLPROPIONIC ACID ESTERS, METHOD FOR OPTICAL RESOLUTION THEREOF AND OPTICALLY ACTIVE SUBSTANCE THEREOF | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |
| US-4709082-A | 2-phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0179487-A1 | 2-Phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | PROC, F12, F2 | CTNNB1 3567/4885ALDH1A1 2372/4885TDP1 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.