SCHEMBL6928110

SCHEMBL6928110

NC(=O)NC(NC(N)=O)NC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.44
TSHR P16473 2/20 0.44
NFKB1 P19838 2/20 0.44
BLM P54132 2/20 0.44
PMP22 Q01453 2/20 0.44
CYP1A2 P05177 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
THPO P40225 1/20 0.44
CA2 P00918 1/20 0.44
CYP3A4 P08684 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
ALDH1A1 P00352 2/20 0.36
OR51E2 Q9H255 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CRBN Q96SW2 1/20 0.35
NPC1 O15118 1/20 0.34
ACHE P22303 1/20 0.33
CAD P27708 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4013459 0.74
SCHEMBL14505490 0.74
SCHEMBL319806 0.74
SCHEMBL9911187 0.74 LMNA (0.41) LMNATSHRNFKB1BLMPMP22
SCHEMBL3064250 0.72
SCHEMBL24463 0.72
SCHEMBL8754819 0.72 LMNA (0.39) LMNATSHRNFKB1BLMPMP22
SCHEMBL4011389 0.72 LMNA (0.47) LMNATSHRNFKB1BLMPMP22
SCHEMBL967147 0.72
SCHEMBL3071346 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6515177-B1 A method of forming a methylol urea prepolymer, comprising the steps of: providing a source of methylol urea and a source of aldehyde and reacting the urea and the aldehyde in the presence of an excess of urea to form the methylol urea THE HOMESTEAD CORPORATION 2003-02-04 US disclosed
US-6432156-B1 SUBSTRATE PARTICLE COATED WITH UREA-FORMALDEHYDE POLYMER AND METHYLENE UREA-TYPE COMPOUND THE HOMESTEAD CORP. 2002-08-13 US disclosed