Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 15/20 | 0.65 |
| ▸ | GABRD | O14764 | 15/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 15/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 15/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 15/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 15/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.65 |
| ▸ | GABRE | P78334 | 15/20 | 0.65 |
| ▸ | GABRA6 | Q16445 | 15/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 15/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 15/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 15/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574674 | 0.82 | GAA (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6927580 | 0.79 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6928492 | 0.76 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13664193 | 0.74 | MAPT (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13664190 | 0.74 | MAPT (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20625312 | 0.71 | MAPT (0.53) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13664197 | 0.70 | CA1 (0.48) | KMT2A | |
| SCHEMBL12998727 | 0.70 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10551874 | 0.70 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13664191 | 0.70 | MAPK14 (0.48) | MAPTGAASRCBRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | claimed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | claimed |
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | disclosed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |