Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GABRP | O00591 | 2/20 | 0.51 |
| ▸ | GABRD | O14764 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.51 |
| ▸ | GABRE | P78334 | 2/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308907 | 0.84 | GAA (0.56) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL6928206 | 0.82 | GABRP (0.65) | GAAMAPTGABRPGABRDGABRA1 | |
| SCHEMBL2546236 | 0.81 | GAA (0.68) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL11546523 | 0.79 | GAA (0.65) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL13860443 | 0.79 | GAA (1.00) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL12998727 | 0.78 | GABRP (0.48) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL3994806 | 0.76 | GAA (0.61) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL8553062 | 0.76 | GAA (0.61) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL2743087 | 0.76 | GAA (0.61) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL3615656 | 0.76 | GAA (0.61) | GAAMAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2600897-A2 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF FRUCTOKINASE | The Regents of the University of Colorado, A Body Corporate (US) | 2013-06-12 | — | — | EP | claimed |
| WO-2012019188-A2 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF FRUCTOKINASE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-02-09 | — | — | WO | claimed |
| US-20250177348-A1 | Methods for Fructokinase Meditation of Alcohol Craving and Alcohol Induced Liver Disease | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2025-06-05 | — | — | US | disclosed |
| US-12161621-B2 | Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2024-12-10 | — | — | US | disclosed |
| US-20210275494-A1 | METHODS FOR FRUCTOKINASE MEDIATION OF ALCOHOL CRAVING AND ALCOHOL INDUCED LIVER DISEASE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2021-09-09 | — | — | US | disclosed |
| WO-2020046481-A2 | METHODS FOR FRUCTOKINASE MEDIATION OF ALCOHOL CRAVING AND ALCOHOL INDUCED LIVER DISEASE | REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2020-03-05 | — | — | WO | disclosed |
| US-9387245-B2 | Methods and compositions for the inhibition of fructokinase | UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-07-12 | — | — | US | disclosed |
| US-9387245-B2 | Methods and compositions for the inhibition of fructokinase | UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-07-12 | — | — | US | disclosed |
| US-9387245-B2 | Methods and compositions for the inhibition of fructokinase | UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-07-12 | — | — | US | disclosed |
| US-20130224218-A1 | Methods and Compositions for the Inhibition of Fructokinase | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130195886-A1 | Methods for Fructanase and Fructokinase Inhibition | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-08-01 | — | — | US | disclosed |
| EP-2600897-A2 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF FRUCTOKINASE | The Regents of the University of Colorado, A Body Corporate (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012019188-A2 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF FRUCTOKINASE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-02-09 | — | — | WO | disclosed |
| EP-0745684-B1 | Method of quantitative determination of peroxides, a peroxidation-active substance or a pyrazolopyridopyridazine derivative | KYOWA MEDEX CO LTD (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5801008-A | Method of quantitative determination of peroxide, a peroxidation-active substance or a pyrazolopyridopyridazine derivative | KYOWA MEDEX CO., LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0745684-A1 | Method of quantitative determination of peroxide, a peroxidation-active substance or a pyrazolopyridopyridazine derivative | KYOWA MEDEX CO., LTD. (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-4065447-A | MONOAZO DYES | SANDOZ LTD. (CH) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12161621-B2 | Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease | KHK, GCK, FN3K | GAA 228/4885MAPT 1991/4885ALDH1A1 842/4885 |
| US-20130195886-A1 | Methods for Fructanase and Fructokinase Inhibition | SI, GCK, FN3K | GAA 31/4885MAPT 3170/4885ALDH1A1 1753/4885 |
| US-20210275494-A1 | METHODS FOR FRUCTOKINASE MEDIATION OF ALCOHOL CRAVING AND ALCOHOL INDUCED LIVER DISEASE | KHK, GCK, FN3K | GAA 225/4885MAPT 1978/4885ALDH1A1 784/4885 |
| US-20130224218-A1 | Methods and Compositions for the Inhibition of Fructokinase | KHK, GCK, HK1 | GAA 183/4885MAPT 1830/4885ALDH1A1 1593/4885 |
| US-20250177348-A1 | Methods for Fructokinase Meditation of Alcohol Craving and Alcohol Induced Liver Disease | KHK, GCK, FN3K | GAA 214/4885MAPT 1117/4885ALDH1A1 1191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.