Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928801 | 0.81 | PKM (0.62) | GAAMAPTSMN1; SMN2 | |
| SCHEMBL4198415 | 0.76 | GAA (0.55) | MCHR1HTR2CSLC2A1GAAMAPT | |
| SCHEMBL6204180 | 0.76 | GAA (0.47) | MCHR1HTR2CGAAMAPT | |
| SCHEMBL6926905 | 0.76 | MCHR1 (0.77) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL2071884 | 0.75 | GAA (0.59) | GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL6922538 | 0.74 | ALDH1A1 (0.41) | MCHR1GAAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6926164 | 0.74 | GAA (0.42) | MCHR1HTR2CGAAMAPT | |
| SCHEMBL6927859 | 0.73 | GAA (0.41) | MCHR1HTR2CGAAMAPT | |
| SCHEMBL6927647 | 0.73 | CYP1A2 (0.59) | MCHR1HTR2CGAAMAPTSMN1; SMN2 | |
| SCHEMBL6807342 | 0.72 | MCHR1 (0.48) | MCHR1HTR2CGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001766-B1 | COMPOUNDS FOR THE TREATMENT OF CCR5-MEDIATED DISEASES | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6515027-B1 | Ligands, agonists or antagonists, of the CC chemokine receptor CC-CKR5 | SMITHKLINE BEECHAM CORP. | 2003-02-04 | — | — | US | disclosed |
| EP-1001766-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-1001766-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999001127-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |