Ethylene Glycol

Ethylene Glycol

SCHEMBL6928253

C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCCc1ccc(O)c(COCc2cc(CCCCCCCCC)ccc2O)c1.OCCO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.49
PTGS2 P35354 3/20 0.49
CYP3A4 P08684 3/20 0.49
ESR1 P03372 2/20 0.49
ADRA2A P08913 2/20 0.49
ADORA3 P0DMS8 2/20 0.49
TACR2 P21452 2/20 0.49
SLC6A2 P23975 2/20 0.49
SLC6A4 P31645 2/20 0.49
SLC6A3 Q01959 2/20 0.49
TP53 P04637 2/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.49
SHBG P04278 1/20 0.49
HSPD1 P10809 1/20 0.49
ADRB3 P13945 1/20 0.49
HTR2C P28335 1/20 0.49
HSPE1 P61604 1/20 0.49
HIF1A Q16665 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6928257 0.86 ALDH1A1 (0.58) KAT8PTGS2CYP3A4ESR1ADRA2A
Ether SCHEMBL6930294 0.82 THRB (0.46) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL9453884 0.81 KAT8 (0.55) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL5635615 0.81 KAT8 (0.58) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL30124210 0.81 KAT8 (0.58) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL1022113 0.80 KAT8 (0.61) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL6212332 0.80 KAT8 (0.61) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL1024221 0.80 KAT8 (0.61) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL11783346 0.80 KAT8 (0.61) KAT8PTGS2CYP3A4ESR1ADRA2A
SCHEMBL1024195 0.80 KAT8 (0.61) KAT8PTGS2CYP3A4ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801117-B1 Antifouling resin composition NIPPON PAINT CO LTD (JP) 2003-11-26 EP disclosed
US-6123755-A DOES NOT ELUTE ANTIFOULING COMPOUNDS, DURABLE NIPPON PAINT CO., LTD. (JP) 2000-09-26 US disclosed
EP-0801117-A2 Antifouling resin composition Nippon Paint Co., Ltd. (JP) 1997-10-15 EP disclosed