SCHEMBL6928263

SCHEMBL6928263

CCOC(=O)C1=NN(c2ccc(OC)cc2)C(=O)C1(O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.46
GAA P10253 4/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 4/20 0.43
HPGD P15428 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPBWR1 P48145 1/20 0.43
MCHR1 Q99705 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
HSD17B10 Q99714 2/20 0.42
POLB P06746 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933815 0.90 RAB9A (0.45) SMN1; SMN2GAAMAPTKMT2ACYP1A2
SCHEMBL6935778 0.87 MEN1 (0.48) SMN1; SMN2GAAMAPTMEN1KMT2A
SCHEMBL6930693 0.86 GAA (0.55) PDE4DSMN1; SMN2GAAMAPTMEN1
SCHEMBL6933158 0.83 MEN1 (0.46) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL6934726 0.78 APP (0.48) SMN1; SMN2GAAMAPTMEN1KMT2A
SCHEMBL6935414 0.78 ELANE (0.44) PDE4DSMN1; SMN2GAAMAPTMEN1
SCHEMBL6935335 0.76 MEN1 (0.46) SMN1; SMN2GAAMAPTMEN1KMT2A
SCHEMBL6933171 0.74 ELANE (0.43) SMN1; SMN2GAAMAPTMEN1KMT2A
SCHEMBL7612002 0.74 PDE4D (0.50) PDE4DSMN1; SMN2GAAMAPTMEN1
SCHEMBL6932885 0.74 MAPT (0.42) SMN1; SMN2GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US claimed
EP-0903342-B1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics OREAL (FR) 2003-12-17 EP disclosed
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US disclosed
EP-0903342-A1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics L'OREAL (FR) 1999-03-24 EP disclosed