Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383277 | 0.95 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL9503922 | 0.91 | ALDH1A1 (0.44) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL9503918 | 0.85 | ALDH1A1 (0.37) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL8610891 | 0.84 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL7925093 | 0.84 | TSHR (0.51) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL10168250 | 0.84 | ALDH1A1 (0.45) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL28432484 | 0.84 | TSHR (0.50) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL181429 | 0.82 | TSHR (0.63) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL223415 | 0.81 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL28830843 | 0.80 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4CA2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610802-B2 | Polymerizing unsatd. monomers with a transition metal catalyst and a coordination compound-forming ligand; filtration using a filter aid having carboxylic acid-, sulfonic acid- or phosphonic acid-containing units | ROHMAX ADDITIVES GMBH (DE) | 2003-08-26 | — | — | US | disclosed |
| US-20030060587-A1 | Process for synthesis of polymer compositions, polymer compositions obtainable by the process, and use of the same | ROHMAX ADDITIVES GMBH (DE) | 2003-03-27 | — | — | US | disclosed |