Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004222 | 1.00 | PTPN22 (0.44) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL146878 | 0.89 | ALDH1A1 (0.44) | PTPN22HSD17B10CYP1A2MAPTWDR5 | |
| SCHEMBL29496111 | 0.89 | ALDH1A1 (0.44) | PTPN22HSD17B10CYP1A2MAPTWDR5 | |
| SCHEMBL29350037 | 0.89 | ALDH1A1 (0.44) | PTPN22HSD17B10CYP1A2MAPTWDR5 | |
| SCHEMBL5107 | 0.89 | ALDH1A1 (0.44) | PTPN22HSD17B10CYP1A2MAPTWDR5 | |
| SCHEMBL10323632 | 0.89 | ALDH1A1 (0.44) | PTPN22HSD17B10CYP1A2MAPTWDR5 | |
| SCHEMBL7117357 | 0.88 | HSP90AA1 (0.41) | PTPN22POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL729691 | 0.88 | ALDH1A1 (0.42) | PTPN22HSD17B10CYP1A2MAPTWDR5 | |
| SCHEMBL3416712 | 0.88 | ALDH1A1 (0.42) | PTPN22HSD17B10CYP1A2MAPTWDR5 | |
| SCHEMBL356363 | 0.88 | ALDH1A1 (0.42) | PTPN22HSD17B10CYP1A2MAPTWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015038872-A1 | BIARYL LIGANDS | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-03-19 | — | — | WO | disclosed |
| EP-1206427-A4 | CHIRAL LIGANDS, TRANSITION-METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | PENN STATE RES FOUND (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-1206427-A1 | CHIRAL LIGANDS, TRANSITION-METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014299-A1 | CHIRAL LIGANDS, TRANSITION-METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-03-01 | — | — | WO | disclosed |